Comparative Study of CNS Effects of Opium in Homeopathic Potencies with Pentazocine in Mice
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1. | Title | Title of document | Comparative Study of CNS Effects of Opium in Homeopathic Potencies with Pentazocine in Mice |
2. | Creator | Author's name, affiliation, country | Karandikar Y. S.; Department of Pharmacology, B.V.D.U. Medical College, Pune, Maharashtra; India |
2. | Creator | Author's name, affiliation, country | Bhagat V. A.; Department of Anatomy, B.V.D.U. Medical College, Pune, Maharashtra; India |
2. | Creator | Author's name, affiliation, country | Mate V. H.; Department of Pharmacology, B.V.D.U. Medical College, Pune, Maharashtra; India |
3. | Subject | Discipline(s) | Medical science,pharmacology |
3. | Subject | Keyword(s) | Opium, Homeopathic Drugs, Locomotor Activity |
3. | Subject | Subject classification | experimental research in Pharmacology andhomeopathy |
4. | Description | Abstract |
Opium is a drug being used in modern medicine as well as in homeopathy. Despite of the same source, both the pathies have different principles and indications. Opium is an alkaloid having main action on CNS. So in this study, we evaluated the effect of different dilutions of Opium in homeopathic potencies on CNS in mice and compared with that of Pentazocine. We divided forty mice of either sex into 7 groups (6c, 30c, 200c, 1 M, 0/1 LM, dispensing alcohol, Pentazocine). Test drugs were given orally. Different actions on CNS were evaluated by using Actophotometer for locomotor activity, Analgesiometer for analgesic activity and Straub test for opioid. Our result showed that pharmacological actions of Opium seen in modern medicine were not seen with different dilutions of Opium, in homeopathic potencies. 30c and 200c dilutions may be having secondary curative that is CNS stimulant action (reversal of CNS depression due to alcohol) as per homeopathic principles.
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5. | Publisher | Organizing agency, location | |
6. | Contributor | Sponsor(s) | |
7. | Date | (YYYY-MM-DD) | 2013-09-07 |
8. | Type | Status & genre | Peer-reviewed Article |
8. | Type | Type | Animal experiment |
9. | Format | File format | |
10. | Identifier | Uniform Resource Identifier | http://medical.cloud-journals.com/index.php/IJAAYUSH/article/view/Med-93 |
11. | Source | Journal/conference title; vol., no. (year) | International Journal of Advanced Ayurveda, Yoga, Unani, Siddha and Homeopathy; Vol 2, No 1 (2013) |
12. | Language | English=en | en |
14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
15. | Rights | Copyright and permissions |
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