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Comparative Study of CNS Effects of Opium in Homeopathic Potencies with Pentazocine in Mice


 
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1. Title Title of document Comparative Study of CNS Effects of Opium in Homeopathic Potencies with Pentazocine in Mice
 
2. Creator Author's name, affiliation, country Karandikar Y. S.; Department of Pharmacology, B.V.D.U. Medical College, Pune, Maharashtra; India
 
2. Creator Author's name, affiliation, country Bhagat V. A.; Department of Anatomy, B.V.D.U. Medical College, Pune, Maharashtra; India
 
2. Creator Author's name, affiliation, country Mate V. H.; Department of Pharmacology, B.V.D.U. Medical College, Pune, Maharashtra; India
 
3. Subject Discipline(s) Medical science,pharmacology
 
3. Subject Keyword(s) Opium, Homeopathic Drugs, Locomotor Activity
 
3. Subject Subject classification experimental research in Pharmacology andhomeopathy
 
4. Description Abstract

Opium is a drug being used in modern medicine as well as in homeopathy. Despite of the same source, both the pathies have different principles and indications. Opium is an alkaloid having main action on CNS. So in this study, we evaluated the effect of different dilutions of Opium in homeopathic potencies on CNS in mice and compared with that of Pentazocine. We divided forty mice of either sex into 7 groups (6c, 30c, 200c, 1 M, 0/1 LM, dispensing alcohol, Pentazocine). Test drugs were given orally. Different actions on CNS were evaluated by using Actophotometer for locomotor activity, Analgesiometer for analgesic activity and Straub test for opioid. Our result showed that pharmacological actions of Opium seen in modern medicine were not seen with different dilutions of Opium, in homeopathic potencies. 30c and 200c dilutions may be having secondary curative that is CNS stimulant action (reversal of CNS depression due to alcohol) as per homeopathic principles.

 
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7. Date (YYYY-MM-DD) 2013-09-07
 
8. Type Status & genre Peer-reviewed Article
 
8. Type Type Animal experiment
 
9. Format File format PDF
 
10. Identifier Uniform Resource Identifier http://medical.cloud-journals.com/index.php/IJAAYUSH/article/view/Med-93
11. Source Journal/conference title; vol., no. (year) International Journal of Advanced Ayurveda, Yoga, Unani, Siddha and Homeopathy; Vol 2, No 1 (2013)
 
12. Language English=en en
 
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