Comparison between the Improvements in Disease Activity Score 28 (DAS28) Using Erythrocyte Sedimentation Rate (DAS28-ESR) and Clinical Parameters in Cases of Waja-al-Mafasil (Rheumatoid Arthritis)
| Dublin Core | PKP Metadata Items | Metadata for this Document | |
| 1. | Title | Title of document | Comparison between the Improvements in Disease Activity Score 28 (DAS28) Using Erythrocyte Sedimentation Rate (DAS28-ESR) and Clinical Parameters in Cases of Waja-al-Mafasil (Rheumatoid Arthritis) |
| 2. | Creator | Author's name, affiliation, country | Mohd. Wasim Ahmad; Research Officer (U), Scientist L-1, Drug Standardization Research Institute (DSRI), Ghaziabad, under CCRUM, Ministry of Ayush, India |
| 2. | Creator | Author's name, affiliation, country | Anirban Goswami; Investigator (Statistics), Regional Research Institute of Unani Medicine, Patna, under CCRUM, Ministry of Ayush, India |
| 2. | Creator | Author's name, affiliation, country | Rajesh .; Research Officer (U), Scientist L-1, Regional Research Institute of Unani Medicine, Patna, under CCRUM, Ministry of Ayush, India |
| 2. | Creator | Author's name, affiliation, country | Md. Ishtiyaque Alam; Research Officer (U), Scientist L-4, Regional Research Institute of Unani Medicine, Patna, under CCRUM, Ministry of Ayush, India |
| 2. | Creator | Author's name, affiliation, country | (doi: 10.23953/cloud.ijaayush.345) |
| 3. | Subject | Discipline(s) | |
| 3. | Subject | Keyword(s) | Clinical Parameters; Disease Activity Score 28 (DAS-28); Improvement; Rheumatoid Arthritis (RA) |
| 4. | Description | Abstract |
Waja-al-Mafasil (Rheumatoid Arthritis) is a progressive, disabling, chronic multisystem disease of unknown cause characterized by pain, swelling and stiffness of synovial joints. The Disease Activity Score (DAS) is a major scoring system for evaluating disease activity of Waja-al-Mafasil (Rheumatoid Arthritis). DAS28 was originally using the erythrocyte sedimentation rate (ESR) as the inflammation marker and named DAS28-ESR. The aim of this study to compare the improvement in disease activity score 28 using erythrocyte sedimentation rate (DAS28-ESR) and clinical parameters in the patients of Rheumatoid Arthritis. Rheumatoid Arthritis patients registered in research OPD was used to calculate DAS28-ESR and clinical assessment. In this study, Majun Jograj Gugal (Semisolid) and Raughan-e-Malkangani (Oil) were administrated to patients for the period of twelve weeks. Improvements of DAS28-ESR were also evaluated according to the European League against Rheumatism response criteria and percentage improvement of clinical parameters in Rheumatoid Arthritis patients. Improvements in DAS28-ESR and Clinical Parameters criteria were compared by Woolf statistical test, Cohen's Kappa (𝜅) statistic for agreement and linear regression analysis. Classification of improvement in DAS28-ESR and clinical parameters among on the demographical characteristics and RA-Factor were generally identical (p-value >0.05) except patients’ nature of work (p-value <0.05). Simple linear regression analysis showed a significant correlation between improvement between DAS28-ESR and clinical parameters (R2 = 0.64; p-value <0.001). The Cohen's Kappa (𝜅) coefficient (95% CI) between of them was 0.43 (0.21 to 0.66), indicating good agreement (p-value <0.001). This study concluded that improvements in Disease Activity Score 28 (DAS28) using erythrocyte sedimentation rate (DAS28-ESR) and Clinical Parameters are same in cases of Rheumatoid Arthritis. |
| 5. | Publisher | Organizing agency, location | |
| 6. | Contributor | Sponsor(s) | |
| 7. | Date | (YYYY-MM-DD) | 2018-04-07 |
| 8. | Type | Status & genre | Peer-reviewed Article |
| 8. | Type | Type | |
| 9. | Format | File format | |
| 10. | Identifier | Uniform Resource Identifier | http://medical.cloud-journals.com/index.php/IJAAYUSH/article/view/417 |
| 11. | Source | Journal/conference title; vol., no. (year) | International Journal of Advanced Ayurveda, Yoga, Unani, Siddha and Homeopathy; Vol 7, No 1 (2018) |
| 12. | Language | English=en | en |
| 14. | Coverage | Geo-spatial location, chronological period, research sample (gender, age, etc.) | |
| 15. | Rights | Copyright and permissions |
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